Preeyam Patel

Monotherapy often leaves a significant portion of IBD patients with suboptimal outcomes, with traditional treatments targeting classic inflammatory pathways and producing low efficacies. This workshop session explores how combination therapies targeting multiple disease pathways can improve response rates, extend remission, and further personalize treatment strategies.

Key topics to be explored:

• Explore strategies to improve overall response rates by targeting multiple disease mechanisms simultaneously
• Use molecular profiling to identify dominant pathways in individual patients and tailor drug combinations for maximum benefit
• Integrating anti-inflammatory and anti-fibrotic approaches to address both acute inflammation and chronic tissue remodeling
• Explore lessons from oncology and translational research to evaluate promsing trial results and cost-effectiveness
• Discuss optimizing trial design and patient selection, with adaptive trial models and data-sharing frameworks to accelerate development