Characterizing Pathogenic Cell Populations in Non-Responder IBD Tissues to Inform Targeted Therapeutic Development
- Characterize pathogenic cell types and molecular factors enriched in non-responder IBD tissues to uncover mechanisms driving treatment resistance
- Leverage tissue-level cellular insights to identify potential therapeutic targets aimed at restoring response or achieving durable remission
- Discuss methodological approaches for profiling non-responder tissues and building a framework linking tissue and blood biomarkers to predict clinical outcomes