Therapeutically Restoring the IL-10 Circuit in Crohn’s Patients
Time: 4:00 pm
day: Pre-Conference Focus Day
Details:
• People who lack sufficient IL-10 signalling develop Crohn’s disease
• Inflammation is complex, driven by hyperinflammatory monocytes and pathogenic Th1/Th17 T cells
• DK410 (VEGFR2) combines IL-10 to block monocytic inflammation and IL-4 to block Th1/Th17 polarization and enriches the cytokines in the neovasculature driven by chronic inflammation
