Pre-Conference Day

Artificial intelligence is transforming the way we understand and manage complex diseases like IBD. This workshop offers a rare opportunity to explore how AI can accelerate discovery, improve patient stratification, and optimize clinical decision making.

Including interactive breakout with live, follow-along tutorial using commercial software to allow participants to build ML Models based on real IBD datasets, making predictions and exploring real-world applications of AI in drug development.

Key Topics to be Explored:

• Investigate innovative use cases that analyze thousands of clinical, molecular, and microbiome data points to identify key predictors of treatment response and relapse
• Using AI trained exclusively on IBD to classify cell types and quantify populations rapidly
• Understand the limitations of AI including hallucinations, bias, and the importance of specialized prompt engineering. Raise concerns of unpredictability and difficulties in validation for clinical use to overcome future roadblocks
• Highlight the potential to compensate for variability, applying computational approaches to analyze endoscopic videos and advanced imaging, linking visual patterns to clinical outcomes
• Apply tools to monitor clinical response and optimize treatment strategies in IBD, enabling more proactive and personalized care in real-world settings

Monotherapy often leaves a significant portion of IBD patients with suboptimal outcomes, with traditional treatments targeting classic inflammatory pathways and producing low efficacies. This workshop session explores how combination therapies targeting multiple disease pathways can improve response rates, extend remission, and further personalize treatment strategies.

Key topics to be explored:

• Explore strategies to improve overall response rates by targeting multiple disease mechanisms simultaneously
• Use molecular profiling to identify dominant pathways in individual patients and tailor drug combinations for maximum benefit
• Integrating anti-inflammatory and anti-fibrotic approaches to address both acute inflammation and chronic tissue remodeling
• Explore lessons from oncology and translational research to evaluate promsing trial results and cost-effectiveness
• Discuss optimizing trial design and patient selection, with adaptive trial models and data-sharing frameworks to accelerate development